Flow of participants through study. All percentages refer to proportion of population defined in preceding row. UK FOCSS, United Kingdom Familial Ovarian Cancer Screening Study; FTC, fallopian tube cancer; OC, ovarian cancer; PPC, primary peritoneal cancer; RRSO, risk-reducing salpingo-oophorectomy. (*) Ineligible on basis of new information regarding diagnoses in family history becoming available subsequent to recruitment. (†)Lost to follow-up: unable to establish current whereabouts; nonresponders: failed to respond despite confirmation of correct contact details. (‡) Reason for surgery pending, but known not to have had OC, FTC, or PPC.