Table 5.
Prognostic Significance of Biologic Markers
| Marker | No. of Patients | CR* |
CR + PR* |
1-Year OS† |
|||||
|---|---|---|---|---|---|---|---|---|---|
| No. | % | P | No. | % | P | % | P | ||
| BCL-2 | 1.000 | .153 | .384 | ||||||
| Negative | 15 | 9 | 60 | 14 | 93.3 | 73.3 | |||
| Positive | 13 | 7 | 53.9 | 9 | 69.2 | 72.7 | |||
| EBER | .354 | .286 | .282 | ||||||
| Negative | 22 | 14 | 63.6 | 19 | 86.4 | 76.2 | |||
| Positive | 6 | 2 | 33.3 | 4 | 66.7 | 60.0 | |||
| GC/non-GC | .300 | 1.000 | .074 | ||||||
| GC | 11 | 8 | 72.7 | 9 | 81.8 | 100 | |||
| Non-GC | 5 | 2 | 40.0 | 4 | 80.0 | 50 | |||
Abbreviations: CR, complete remission; EBER, Epstein-Barr virus RNA; GC, germinal center B cell–like; OS, overall survival; PR, partial response.
*
Fisher's exact test.
†
Log-rank test.