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. 2012 Dec 27;2:190. doi: 10.3389/fonc.2012.00190

Table 1.

Recommendations for Cancer screening as suggested by the American Cancer Society.

Screening exam Recommendations (1999–2010)
Breast cancer screening Mammography (an digital or film x ray picture of the breast) Women ≥40 years should have mammograms every 1–2 years
Women with a higher than average risk of breast cancer should discuss frequency of, and age at first screening with their health care providers
Clinical breast exam Every 3 years for women in their 20s and 30s and every year for women ≥40 years
Cervical cancer screening Pap test* 1999 Sexually active women or those ≥18 years, annual Pap test and pelvic examination. After more than 3 consecutive satisfactory normal annual examinations, the Pap test may be performed less frequently at the discretion of the physician
2002 At least 3 years after first vaginal intercourse, but no later than 21 years old, women should have regular Pap tests every 1 year or every 2 years with newer liquid-based test. Women ≥30 with 3 consecutive normal Pap test results may get screened every 2–3 years
Women >30 years may also get screened every 3 years with either the conventional or liquid-based Pap test, in addition to the human papillomavirus (HPV) test
Women ≥70 years with 3 or more consecutive normal Pap tests and no abnormal Pap test results in the last 10 years may discontinue testing
Women who have had a total hysterectomy for non-cancer related reasons may discontinue testing
2009 Screening should begin at age 21
Women 21–29 years should have Pap test every 3 years. If Pap test result is abnormal then women should have a HPV test
Women 30–65 years should have both a Pap test and an HPV test every 5 years. It is also okay to have a Pap test alone every 3 years
Women >65 years who have had regular screenings with normal results should not be screened for cervical cancer
However those who have been diagnosed with cervical pre-cancer should continue to be screened
Colorectal screening Men and women ≥50 years
Flexible sigmoidoscopy Every 5 years, or
Colonoscopy Every 10 years, or
CT colonography (virtual colonoscopy) Every 5 years
Double-contrast barium enema Every 5 years
Fecal occult blood test (gFOBT) Annually, or
Fecal immunochemical test (iFOBT/FIT) Annually, or
Stool DNA test (sDNA) Interval uncertain (possibly 3–5 years)
Prostate cancer screening Prostate specific antigen (PSA) blood test/velocity test [How PSA measures rise over time] Discuss with physician the pros and cons of receiving a baseline PSA and follow-up test if necessary
PSA density test [Ratio of PSA level to size of prostate gland] Men at higher than normal risk (Blacks, men whose father, brother or son have been diagnosed with prostate cancer) discuss screening with physician at 45 years
Percent-free PSA [Ratio of unattached PSA in blood to total PSA] Men ≥50 years discuss the harms and benefits of PSA screening with physician
Age-specific PSA range Men with a previous PSA of ≥4 ng/ml in the blood, should be retested if discussion with physician dictates a necessity
Digital rectal exam As recommended by physician

*In 2009 the recommendation for cervical cancer screening changed to pap tests every three years beginning at age 21. Recommendations now include HPV testing every 5 years among women 30–65 years. HPV testing was not included in our analyses. If test is positive, a colonoscopy should be done. A single test done in the doctor’s office is not adequate for testing. A colonoscopy should be done if the test is positive.