Table 1.
Disease | Results | Comments | Ref. |
Aging | ↓ EPCs proliferation | [20,22] | |
↓ EPCs migration | |||
↓ EPCs survival | |||
Coronary heart disease | ↓ EPC activity | [29] | |
↓ EPC migratory capacity | |||
CHF | ↑ EPC levels in mild stages[34,35] | [34-36] | |
↑ EPC levels in acute exacerbation[36] | |||
↑ Late apoptotic progenitors[35] | |||
↓ EPC levels in advanced stages[34,35] | |||
LVADs | ↑ EPC levels | [38,39] | |
PAH | ↑ EPC levels[42,45,46] | Conflicting results | [42-46] |
↓ EPC levels[43,44] | |||
Critical illness | ↑ EPC levels in sepsis and septic shock[47,49] | [47-49] | |
↑ EPC levels in early acute lung injury[48] | |||
COPD | ↑ EPC levels[52] | Conflicting results | [52-56] |
↓ EPC levels[53,54] | |||
↑ EPC levels in exacerbation of COPD[55] | |||
↓ EPC mobilization and colony-forming capacity[56] | |||
OSA | ↑ EPC levels[58,60] | Conflicting results | [57-60] |
↓ EPC levels[59] | |||
- No difference[57] | |||
Diabetes mellitus type Iand II | ↓ EPC levels | [61-65] | |
Cerebrovascular disease | ↓ EPC levels in stroke[66] | [66-69] | |
- No difference in ischemic stroke[67] | |||
↑ EPC levels in acute ischemic stroke[67] | |||
↓ EPC levels in atherothrombotic cerebral ischemic event[68] | |||
↓ EPC colony forming in acute stroke[69] | |||
PAD | ↑ EPC levels in moderate phase | [71,72] | |
↑ EPC levels in advance phase | |||
Arterial hypertension | ↑ EPC levels in early stage of hypertension[73] | [19,73,74] | |
↓ EPC migratory capacity in CAD and hypertension[19] | |||
- No difference on EPC levels in pre-hypertensive and hypertensive[74] | |||
Obesity | ↓ EPC levels[75-77] | [75-79] | |
↓ EPC colony forming capacity[76] |
EPC: Endothelial progenitor cell; CHF: Chronic heart failure; LVAD: Left ventricular assist device; PAH: Pulmonary arterial hypertension; COPD: Chronic obstructive pulmonary disease; OSA: Obstructive sleep apnea; PAD: Peripheral arterial disease; CAD: Coronary artery disease.