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. 2004 Mar;48(3):961–969. doi: 10.1128/AAC.48.3.961-969.2004

TABLE 3.

In vitro peptidoglycan biosynthesis with membrane preparations from B. megateriuma

Inhibitorb Peptidoglycan synthesis (%) by B. megateriumc
None (control) 100
Tunicamycin 0
Moenomycin 17
Arylalkylidene rhodanine derivative 1 61
Arylalkylidene iminothiazolidin-4-ones
    11 57
    13 64
    16 63
a

Peptidoglycan synthesis started with UDP-MurNAc-pentapeptide and UDP-[14C]-GlcNAc as substrates.

b

Each inhibitor was used at a concentration of 100 μg/ml.

c

The total incorporation of radioactive S in peptidoglycan in the control experiment without inhibitor was 1.5 pmol (12%).