Figure 3. A: The positive signal of RALDH₂ protein, as brown-yellowish granules, was localized in retinal nerve fiber layer(RNFL), inner plexiform layer(IPL) and out-edge of outer nuclear layer(ONL) in guinea pig. However, no positive signal was found in choroid; B: Compared with the normal control, the increase of retinal RALDH₂ protein was found in the lens-induced eyes. The positive signal was localized in the RNFL, IPL, outer plexiform layer(OPL) and out-edge of ONL, and no positive signal was found in choroid; C: Compared with the lens-inducation, the decrease of retinal RALDH₂ protein was found in the RNFL, IPL and out-edge of ONL in the recovering group. No positive signal was found in OPL and choroid. SP×600.