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. Author manuscript; available in PMC: 2012 Dec 27.
Published in final edited form as: J Cell Physiol. 2008 Dec;217(3):752–758. doi: 10.1002/jcp.21550

Figure 6. Survivin is a PAK1 Downstream Effector.

Figure 6

(A and B) Day 4 mature osteoclasts were infected with vector control, caPAK1, dnSurvivin, or caPAK1 and dnSurvivin adenoviruses for eighteen hours. Following infection, osteoclasts were serum starved and treated with M-CSF for eight hours. Shown are (A) Percent Apoptotic Osteoclasts and (B) Total Osteoclasts. *p<0.05 compared to vector infection.