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. Author manuscript; available in PMC: 2012 Dec 27.
Published in final edited form as: Nature. 2012 Oct 24;491(7424):399–405. doi: 10.1038/nature11547

Figure 1. Mutations and copy number variation in axon guidance genes.

Figure 1

Axon guidance pathway genes with recurrent mutations and/or copy-number changes defined by GISTIC2.0 analysis (Q < 0.2), and manually reviewed for focal alterations. a, SNV and CNV frequency per patient with gene-centric summary (left) and patient-centric summary (top); numbers of patients with mutations and proportion of each event are presented. Please see Supplementary Table 4 for further details. b, Clinico-pathological variables for individual patients. APGI, Australian Pancreatic Cancer Genome Initiative; BCM, Baylor College of Medicine; IPMN, intraductal papillary mucinous neoplasm; Mod, moderately differentiated; OICR, Ontario Institute for Cancer Research; PDAC, pancreatic ductal adenocarcinoma; Undiff, undifferentiated.