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. 2012 Jun 5;33(24):3034–3045. doi: 10.1093/eurheartj/ehs113

Table 3.

Factors predicting publication

Parameters No. of studies published No. of studies not published Publication Rate (% submitteda) Univ. reg. OR, 95% CI (P) Multiv. reg. OR, 95% CI (P)
Type of research
 Clinical 251 648 27.9 Ref. Ref.
 Basic 42 61 40.8 1.72, 1.13–2.61 (0.012) 2.11, 1.34–3.34 (0.001)

Type of institution
 Not university-affiliated 43 149 22.4 Ref. Ref.
 University-affiliated 250 560 30.9 1.53, 1.06–2.22 (0.025) 1.62, 1.09–2.43 (0.018)

Study design (clinical) (0.014) (0.279)
 Restrospective 124 370 25.1 Ref. Ref.
 Prospective non-RCT 90 200 31.0 1.32, 0.96–1.82 (0.090) 1.44, 1.03–2.02 (0.032)
 RCT 22 43 33.8 1.53, 0.88–2.65 (0.133) 1.48, 0.84–2.61 (0.181)
 Meta-Analysis 4 2 66.7 5.97, 1.08–32.98 (0.041) 0.0 (1.000)
 Systematic Review 0 2 0.0 0.0 (1.000) 0.0 (1.000)
 Other 11 31 26.2 n.a. n.a.

Number of patients (clin.)b
 <100 120 318 27.4 Ref.
 ≥100 117 298 28.2 1.08, 0.80–1.46 (0.068)

Study field (clinical) (0.228)
 Cardiac imaging, computational, acute cardiac care 32 71 31.1 Ref.
 Rhythmology 30 97 23.6 0.71, 0.41–1.25 (0.236)
 Heart failure, left ventricular function, valvular disease, pulmonary circulation 40 112 26.3 0.86, 0.51–1.47 (0.588)
 Coronary artery disease, ischaemia 39 93 29.5 0.94, 0.55–1.61 (0.821)
 Interventional cardiology, peripheral circulation, stroke 27 67 28.7 0.86, 0.47–1.55 (0.610)
 Exercise, prevention, epidemiology, pharmacology, nursing 36 110 24.7 0.76, 0.44–1.32 (0.328)
 Hypertension, myocardial and pericardial disease, cardiovascular surgery 29 66 30.5 1.12, 0.68–2.12 (0.533)
 Other 18 32 36.0 n.a. n.a.

Gender first authorc
 Male 217 506 30.0 Ref. Ref.
 Female 71 190 27.2 0.88, 0.63–1.18 (0.352) 0.94, 0.67–1.32 (0.723)

Gender last authord
 Male 259 583 30.8 Ref. Ref.
 Female 25 106 19.1 0.54, 0.34–0.85 (0.008) 0.52, 0.32–0.85 (0.010)

OR, odds ratio; CI, confidence interval; RCT, randomized controlled trial; ref., reference variable for odds ratio calculation; n.a., not applicable. Analyses performed on representative 10% selection (n = 1002), margin of error < 0.01. Backward conditional variable exclusion, c-statistic = 0.757.

Bold value indicates statistically significant findings.

aPercent submitted refers to submissions to the ESC Congress.

bIn 46 clinical studies, no information on the number of patients was provided.

cIn 18 studies, no gender for the first author could be identified.

dIn 29 studies, no gender for the last author could be identified.