Table 4.
Parameters | Articles cited 10× or more in 2 years [% of published (n/n)] | Univariate reg. OR, 95% CI (P) | Multivatiate reg. OR, 95% CI (P) |
---|---|---|---|
Type of research | |||
Clinical | 14.3 (36/251) | Ref. | |
Basic | 11.9 (5/42) | 0.73, 0.27–1.98 (0.537) | |
Type of institution | |||
Not university-affiliated | 7.0 (3/43) | Ref. | |
University-affiliated | 15.2 (38/250) | 2.63, 0.77–8.90 (0.121) | |
Study design (clinical) | (0.001) | (0.004) | |
Restrospective | 6.5 (8/124) | Ref. | Ref. |
Prospective non-RCT | 18.9 (17/90) | 3.39, 1.457.90 (0.005) | 2.57, 1.20–5.68 (0.018) |
RCT | 40.9 (9/22) | 8.77, 2.96–26.02 (<0.001) | 6.82, 2.46–21.12 (0.001) |
Meta Analysis | 50.0 (2/4) | 12.67, 1.59–100.80 (0.016) | 16.30, 1.20–281.94 (0.044) |
Systematic Review | — | — | — |
Other | 0.0 (0/11) | n.a. | n.a. |
Number of patients (clinical)a | |||
<100 | 12.5 (15/120) | Ref. | |
≥100 | 17.9 (21/117) | 1.33, 076–2.67 (0.414) | |
Study field (clinical) | (0.028) | (0.114) | |
Cardiac imaging, computational, acute cardiac care | 17.7 (5/32) | Ref. | Ref. |
Rhythmology | 13.3 (4/30) | 0.64, 0.16–2.53 (0.528) | 0.59, 0.14–2.40 (0.475) |
Heart failure, left ventricular function, valvular disease, pulmonary circulation | 7.5 (3/40) | 0.33, 0.08–1.44 (0.142) | 0.29, 0.06–1.31 (0.119) |
Coronary artery disease, ischemia | 30.8 (12/39) | 1.96, 0.66–5.84 (0.229) | .79, 0.54–5.37 (0.331) |
Interventional cardiology, peripheral circulation, stroke | 25.9 (7/27) | 1.86, 0.56–2.49 (0.310) | .44, 0.44–5.72 (0.582) |
Exercise, prevention, epidemiology, pharmacology, nursing | 56 (2/36) | 0.69, 0.19–2.49 (0.567) | 0.71, 0.19–2.95 (0.630) |
Hypertension, myocardial and peri-cardial disease, cardiovascular surgery | 6.9 (2/29) | 0.42, 0.10–1.62 (0.254) | 0.39, 0.09–1.90 (0.230) |
Other | 5.6 (1/18) | n.a. | n.a. |
Gender first authorb | |||
Male | 14.3 (31/217) | Ref. | Ref. |
Female | 18.3 (13/71) | 1.34, 0.66–2.73 (0.423) | 0.0 (1.00) |
Gender last authorc | |||
Male | 16.6 (43/259) | Ref. | |
Female | 4.0 (1/25) | 0.22, 0.03–1.66 (0.142) |
OR, odds ratio; CI, confidence interval; RCT, randomized controlled trial; ref., reference variable for odds ratio calculation, n.a., not applicable. Analyses performed on representative 10% selection (n = 1002), margin of error <0.01. Backward conditional variable exclusion, c-statistic = 0.570.
Bold value indicates statistically significant findings.
aIn 46 clinical studies, no information on the number of patients was provided.
bIn 18 studies, no gender for the first author could be identified.
cIn 29 studies, no gender for the last author could be identified.