Table 2.
Grade 0 | Grade 1 | Grade 2 | Grade 3 | No RPE disruption | RPE disruption | |
---|---|---|---|---|---|---|
Threshold lesions | 1/51 (2%) | 3/51 (6%) | 5/51 (10%) | 42/51 (82%) | 29/51 (57%) | 22/51 (43%) |
Subthreshold lesions | 236/333 (71%) | 15/333 (4%) | 33/333 (10%) | 49/333 (15%) | 321/333 (96%) | 12/333 (4%) |
* p < 0.0001 | * p < 0.0001 |
Grade 0: no changes. Grade 1: mild, discrete disruption along the junction of the inner segments/outer segments (IS/OS) of the photoreceptors. Grade 2: clear focal disruption of the IS/OS. Grade 3: clear focal disruption of the IS/OS and abrupt thinning and increased reflectivity of the corresponding outer nuclear layer. RPE: retinal pigment epithelium.
Generalized Estimating Equations Analysis, (GEE).