Table 1.
Demographic Characteristics of Rheumatoid Arthritis Patients Included in the Study
| Clinical feature | % (n/N) | With CV events, % (n) | Without CV events, % (n) | p-value |
|---|---|---|---|---|
| Main characteristics | ||||
| Women | 74.09 (1201/1621) | 62.61 (210) | 77.06 (991) | <10−6 |
| Age of patients at the time of disease diagnosis, years, median (IQR) | 54 (43–64) | 62.4 (53.6–70) | 52 (41–61) | <10–3 |
| Time follow-up, years, median (IQR) | 10.4 (5–17) | 11 (6–19) | 10 (5–16) | 0.30 |
| Anti-CCP-positive | 57.62 (760/1319) | 51.39 (129) | 59.08 (631) | 0.017 |
| Rheumatoid factor-positive | 69.16 (1101/1592) | 69.11 (217) | 69.17 (884) | 0.98 |
| Cardiovascular risk factors | ||||
| Hypertension | 40.87 (658/1610) | 66.36 (219) | 34.30 (439) | <10–7 |
| Diabetes mellitus | 13.33 (214/1605) | 23.40 (77) | 10.74 (137) | <10–7 |
| Dyslipidemia | 38.93 (626/1608) | 55.39 (185) | 34.62 (441) | <10–7 |
| Obesity | 22.95 (350/1525) | 28.66 (88) | 21.51 (262) | 0.008 |
| Smoking habit | 28.77 (443/1540) | 34.07 (108) | 27.39 (335) | 0.019 |
| Cardiovascular events | 20.79 (337/1621) | 100 (337) | NA | |
Except where indicated otherwise, values are % (n/N).
CV, cardiovascular; IQR, interquartile range; Anti-CCP, anti-cyclic citrullinated peptide antibodies; NA, not applicable.