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. 2012 Sep 14;19(1-2):199–210. doi: 10.1089/ten.tea.2012.0182

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Copyright 2013, Mary Ann Liebert, Inc.

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FIG. 5. — Tendon constructs demonstrate features of embryonic tendon. Ultrastructural analysis of progenitor-derived tendon constructs. Tendon constructs assembled collagen fibrils and fibers (A, B), similar to those in a developing P3 Achilles tendon (C). Dashed white boxes (A, B, C) represent regions further magnified below (D, E, F, respectively). The dashed black line encircles a region exemplifying fibrils packing to form fibers. The insets in panels D–F magnify the fibril structure within the black boxes of the same panels. The insets show fibril structure in the constructs relative to the developing tendon. Relatively small diameter fibrils with a homogeneous distribution of diameters are observed in all cases. [Bar: 2 μm (A, B, C); 1 μm (D, E, F), 100 nm (Insets in D, E, F)].