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. 2012 Sep 14;19(1-2):199–210. doi: 10.1089/ten.tea.2012.0182

Table 1.

Markers Utilized to Characterize Tendon Stem/Progenitor Cells120

Marker Gene Symbol Marker Specification Assay Technique References
Cd18 antigen (Integrin beta-2) Cd18 Leukocyte adhesion molecule FCA 21, 22
Hematopoietic progenitor cell antigen Cd34 Cd34 Hematopoietic and vascular stem cell marker FCA 2325
Cd44 antigen (Indian blood group) Cd44 Hyaluronic acid receptor; T lymphocyte and mesenchymal stem cell marker FCA, RT-qPCR 2628
Cd90.2 antigen (Thy-1 cell surface antigen, allele 2) Cd90.2 Fibroblast, epithelial cell, thymocyte, epithelial T lymphocyte, mesenchymal stem cell, and neuron marker in mice FCA, RT-qPCR 2933
Cd133 antigen (Prominin-1) Cd133 Neural, endothelial, epithelial, and pericyte stem cell marker FCA, RT-qPCR 3436
Endomucin Emcn Vascular endothelial marker RT-qPCR 3740
Guanine nucleotide-binding protein-like 3 (Nucleostemin) Gnl3 General stem cell marker; detected in bone marrow stroma, thyroid side population, and tendon stem cells RT-qPCR 4143
Musashi-1 Msi1 Muscle, neural, and pericyte stem cell marker RT-qPCR 36, 4345
Stem cell antigen-1 Sca1 General stem cell marker FCA 4649
Scleraxis Scx Tendon marker RT-qPCR 50, 51
Tenomodulin Tnmd Tendon marker RT-qPCR 37, 51

FCA, flow cytometric analysis; RT-qPCR, real-time quantitative polymerase chain reaction.