Table 1.

Comparison of alignment sizes for the four largest Rfam families between Rfam 10.1, full alignments and genome-based alignments

Family	Description	Number of sequences in full, Rfam 10.1	Number of sequences in full, Rfam 11.0	Number of sequences in genome-based alignment
RF00005	tRNA	1 101 833	2 106 268	298 470
RF00177	Bacterial small subunit ribosomal RNA	343 886	744 528	7429
RF01959	Archaeal small subunit ribosomal RNA	9072	881 056	7394
RF01960	Eukaryotic small subunit ribosomal RNA	45 117	65 901	425