Figure 3.

Equistructural sites for hSOD (PDB code 2SOD). The site in 2SOD has eight groups of equistructural sites, including its own group, encompassing a total of 579 sites. Only one representative for each group is shown. All sites are displayed using a cartoon representation of the protein backbone, whereas the metal ions are represented as spheres. The color code for the metal ions is as follows: gray-zinc, gold-copper, pink-cobalt and light yellow-cadmium. (A) Superimposition of all sites. Each site maintains the same color as in its individual panel; (B) 2SOD; (C) 2C9S; (D) 1E9P; (E) 1MFM; (F) 1Q0E (copper site); (G) 1COB; (H) 3H2P; and (I) 1Q0E (zinc site). (C) and (F) are equistructural to the left half of the full site (see panel A), whereas (I) is equistructural to the right half of the full site.