Table 1.
Demographic characteristics and comorbid medical disorders in patients with herpes zoster and the matched-control cohort
| Variable | Patients with herpes zoster | Matched- control subjects | Odds ratio | 95% CI | Pvalue |
|---|---|---|---|---|---|
| Total |
42,498 |
169,983 |
|
|
|
| Follow-up |
|
|
- |
- |
- |
| Total person-years |
168,992 |
684,001 |
|
|
|
| Average person-years |
3.976 |
4.024 |
|
|
|
| Sex |
|
|
- |
- |
0.9874 |
| Female |
52.4 |
52.4 |
|
|
|
| Male |
47.6 |
47.6 |
|
|
|
| Age, years-old |
|
|
- |
- |
1.0000 |
| >= 60 |
40.0 |
40.0 |
|
|
|
| 50-59 |
19.6 |
19.6 |
|
|
|
| 40-49 |
12.9 |
12.9 |
|
|
|
| 30-39 |
10.7 |
10.7 |
|
|
|
| < 30 |
16.6 |
16.6 |
|
|
|
| Comorbidities (%) |
|
|
|
|
|
| Myocardial infarct |
1.4 |
1.2 |
1.12 |
0.95-1.33 |
0.1846 |
| Congestive heart failure |
4.6 |
3.7 |
1.28 |
1.18-1.39 |
<0.0001 |
| Peripheral vascular disease |
2.0 |
1.6 |
1.32 |
1.15-1.51 |
<0.0001 |
| Cerebrovascular disease |
10.5 |
9.5 |
1.19 |
1.13-1.25 |
<0.0001 |
| Dementia |
1.3 |
1.4 |
1.12 |
0.99-1.27 |
0.0667 |
| Chronic pulmonary disease |
29.6 |
24.6 |
1.38 |
1.33-1.43 |
<0.0001 |
| Rheumatologic disease |
4.2 |
2.9 |
1.92 |
1.74-2.10 |
<0.0001 |
| Peptic ulcer disease |
25.7 |
21.2 |
1.40 |
1.35-1.45 |
<0.0001 |
| Mild liver disease |
18.0 |
15.0 |
1.33 |
1.27-1.39 |
<0.0001 |
| Diabetes (mild to moderate) |
13.3 |
11.1 |
1.33 |
1.28-1.39 |
<0.0001 |
| Diabetes (with chronic complications) |
4.0 |
3.2 |
1.36 |
1.26-1.47 |
<0.0001 |
| Hemiplegia or paraplegia |
1.0 |
1.1 |
1.13 |
0.94-1.36 |
0.1897 |
| Renal disease |
6.0 |
4.8 |
1.43 |
1.33-1.54 |
<0.0001 |
| Moderate or severe liver disease | 0.4 | 0.4 | 1.09 | 0.82-1.45 | 0.9568 |