Table 1.
Patients characteristics
|
Total patients n=75 |
|
|||
---|---|---|---|---|---|
Primary n=41 | Recurrence n=34 | ||||
Age |
Median (years), range |
57.3 |
40.2-79.2 |
57.7 |
38.4-79.9 |
|
|
n |
[%] |
n |
[%] |
Gender |
male |
20 |
48.8 |
15 |
44.1 |
|
female |
21 |
51.2 |
19 |
55.9 |
Primary tumour |
Non-small cell lung cancer |
22 |
53.6 |
11 |
32.4 |
|
Breast cancer |
5 |
12.2 |
12 |
35.3 |
|
Malignant melanoma |
6 |
14.6 |
3 |
8.8 |
|
Renal cell carcinoma |
4 |
9.8 |
2 |
5.9 |
|
Small cell lung cancer |
0 |
0 |
5 |
14.7 |
|
Others |
4 |
9.8 |
1 |
2.9 |
RPA-classification |
1 |
7 |
17.1 |
13 |
38.2 |
|
2 |
34 |
82.9 |
21 |
61.8 |
|
3 |
0 |
0 |
0 |
0 |
Extracranial tumour status |
in remission |
5 |
12.2 |
11 |
32.4 |
|
detectable, stable disease |
10 |
24.4 |
8 |
23.5 |
|
progressive |
26 |
63.4 |
15 |
44.1 |
Metastases treated with hfSRT (patients) |
1 |
32 |
78.0 |
19 |
55.9 |
|
2 |
7 |
17.1 |
9 |
26.5 |
|
3 |
2 |
4.9 |
5 |
14.7 |
|
4 |
0 |
0 |
1 |
2.9 |
Time between diagnosis of primary tumour
and brain metastasis |
Median (months), range |
12.5 |
0-166.4 |
12.3 |
0-337.7 |
Time between diagnosis of brain metastasis
and start of hfSRT |
Median (month), range |
1.4 |
0.2-39.9 |
11.4 |
0.5-37.9 |
Intervall between WBRT and start of hfSRT | Median (month), range | 0 | 0 | 12.7 | 0.5-28.8 |