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Comparison of 2-tiered and 3-tiered imputation framework. The 2-tiered framework is composed of top tier (reference panel) and lower tier (test panel). Three separate test panels (bottom tier) using three SNP densities, viz. Bovine3K, BovineLD 7K and 50K, were analysed. In 3-tiered framework an additional panel of 2205 samples with 50K genotypes is included as middle tier.
