Skip to main content
. 2012 Dec 27;8(12):e1002805. doi: 10.1371/journal.pcbi.1002805

Table 1. Alphabetical List of Popular Metabolic Pathway Databases.

Database Name URL or Web Address Comments
HumanCyc (Encylopedia of Human Metabolic Pathways) http://humancyc.org/ -MetaCyc adopted to human metabolism-No disease or drug pathways
KEGG (Kyoto Encyclopedia of Genes and Genomes) http://www.genome.jp/kegg/ -Best known and among the most complete metabolic pathway databases-Covers many organisms-A Few disease and drug pathways
The Medical Biochemistry Page http://themedicalbiochemistrypage.org/ -Simple metabolic pathway diagrams with extensive explanations-A few drug and disease pathways
MetaCyc (Encyclopedia of Metabolic Pathways) http://metacyc.org/ -Similar to KEGG in coverage, but different emphasis-Well referenced-No disease or drug pathways
Reactome (A Curated Knowledgebase of Pathways) http://www.reactome.org/ -Pathway database with more advanced query features-Not as complete as KEGG or MetaCyc
Roche Applied Sciences Biochemical Pathways Chart http://www.expasy.org/cgi-bin/search-biochem-index -The old metabolism standard (on line)-Describes most human metabolism
Small Molecule Pathway Database (SMPDB) http://www.smpdb.ca/ -Pathway database with disease, drug and metabolic pathways for humans-Extensive search, analysis and visualization tools
Wikipathways http://www.wikipathways.org -Community annotated pathway database for 19 model organisms-Contains 175 human pathways-Few drug or disease pathways