Table 3.
Results of direct comparisons of ALS patients and correlation analysis
| Side | Cluster size | x | y | z | T | p | |
|---|---|---|---|---|---|---|---|
|
Paired t-test FA T0 / Follow-up |
|
|
|
|
|
|
|
| Temporal Lobe, Superior Temporal Gyrus, GM, BA 39 |
l |
879 |
-49 |
-62 |
28 |
7.5 |
0.001* |
| Temporal Lobe, Superior Temporal Gyrus, GM, BA 39 |
l |
|
-56 |
-64 |
16 |
4.82 |
0.033* |
| Parietal Lobe, Supramarginal Gyrus, GM, BA 40 |
l |
|
-58 |
-61 |
30 |
4.19 |
0.075* |
| Cerebellum, Posterior Lobe, Declive |
r |
921 |
24 |
-59 |
-25 |
6.88 |
0.002* |
| Cerebellum, Anterior Lobe, Culmen |
r |
|
34 |
-52 |
-21 |
4.25 |
0.07* |
| Precentral Gyrus, WM |
r |
743 |
44 |
-9 |
41 |
6.67 |
0.003* |
| Precentral Gyrus, WM |
r |
|
53 |
-6 |
43 |
5.56 |
0.012* |
| Superior Temporal Gyrus, WM |
r |
2014 |
65 |
-39 |
10 |
6.36 |
0.004* |
| Superior Temporal Gyrus, GM, BA 22 |
r |
|
61 |
-59 |
16 |
5.95 |
0.008* |
| Superior Temporal Gyrus, GM, BA 22 |
r |
|
65 |
-48 |
20 |
5.12 |
0.022* |
| Parietal Lobe, Precuneus, WM |
r |
582 |
35 |
-74 |
39 |
6.21 |
0.005* |
| Brainstem, Midbrain, CST |
r |
270 |
16 |
-16 |
-17 |
5.89 |
0.008* |
| Temporal Lobe |
r |
756 |
44 |
8 |
-42 |
5.72 |
0.01* |
| Superior Frontal Gyrus, WM |
r |
221 |
35 |
39 |
35 |
5.27 |
0.018* |
| Middle Frontal Gyrus, subgyral, WM |
r |
|
29 |
34 |
31 |
4.76 |
0.035* |
| Superior Frontal Gyrus, GM, BA 11 |
r |
487 |
28 |
45 |
-18 |
4.90 |
0.03* |
| Temporal Lobe, Middle Temporal Gyrus, WM |
r |
253 |
60 |
-7 |
-9 |
4.77 |
0.035* |
| Temporal Lobe, Superior Temporal Gyrus, WM |
r |
|
57 |
-2 |
3 |
4.33 |
0.063* |
|
Paired t-test ADC T0 / Follow-up |
|
|
|
|
|
|
|
| Extra-Nuclear, WM, External capsule |
l |
2054 |
-28 |
2 |
-3 |
6.38 |
0.003* |
| Extra-Nuclear, WM, External capsule |
l |
|
-29 |
-15 |
11 |
6.16 |
0.004* |
| Extra-Nuclear, WM, External capsule |
l |
|
-25 |
-1 |
8 |
5.5 |
0.01* |
| Extra-Nuclear, WM, Internal capsule | l | 383 | -19 | 8 | 3 | 5.94 | 0.005* |
Ordered by descending T-values. R=right; L=left, * SVC 10mm (FWE).