Table 4.
Side | Cluster size | x | y | z | T | p | |
---|---|---|---|---|---|---|---|
T0 FA correlation with ALSFRS-R |
|
|
|
|
|
|
|
Right Brainstem, Midbrain |
r |
233 |
10 |
-24 |
-21 |
4.41 |
0.019* |
Cerebellum, Posterior Lobe, Declive |
r |
251 |
13 |
-58 |
-19 |
3.99 |
0.04* |
T0 FA correlation with disease duration |
|
|
|
|
|
|
|
Precentral Gyrus, WM, below BA 6 |
r |
596 |
4 |
-27 |
70 |
4.93 |
0.007* |
Precentral Gyrus, subgyral, WM, Corona radiata |
r |
|
6 |
-30 |
61 |
4.52 |
0.014* |
Sub-lobar, WM, CST, Internal capsule |
l |
867 |
-31 |
-26 |
17 |
4.58 |
0.013* |
Sub-lobar, WM, CST, Internal capsule |
l |
|
-30 |
-18 |
15 |
4.47 |
0.017* |
Cerebellum, Anterior Lobe, Culmen |
r |
317 |
12 |
-56 |
-15 |
4.56 |
0.014* |
Sub-lobar, WM, CST, Corona radiata |
l |
202 |
-13 |
-29 |
51 |
4.37 |
0.02* |
T0 FA correlation with SF36 |
|
|
|
|
|
|
|
Cerebellum, Anterior Lobe, Culmen |
r |
715 |
19 |
-43 |
-27 |
5.24 |
0.004* |
Cerebellum, Anterior Lobe |
r |
|
10 |
-42 |
-33 |
4.4 |
0.019* |
Cerebellum, Anterior Lobe |
l |
561 |
-10 |
-41 |
-33 |
4.84 |
0.008* |
Cerebellum, Anterior Lobe, Culmen |
l |
|
-16 |
-42 |
-27 |
4.22 |
0.027* |
Follow-up FA correlation with ALSFRS-R |
|
|
|
|
|
|
|
Precentral Gyrus, subgyral, WM, BA 6 |
r |
469 |
50 |
2 |
38 |
6.35 |
0.006* |
Precentral Gyrus, subgyral, WM, BA 6 |
r |
|
46 |
-5 |
46 |
6.11 |
0.008* |
Frontal Lobe, Middle Frontal Gyrus, WM |
r |
233 |
33 |
13 |
50 |
5.99 |
0.01* |
Precentral Gyrus, WM, Corona radiata |
r |
417 |
29 |
-15 |
56 |
5.87 |
0.011* |
Precentral Gyrus, WM, Corona radiata |
l |
219 |
-16 |
-12 |
59 |
5.01 |
0.014* |
Follow-up FA correlation with disease duration |
|
|
|
|
|
|
|
Capsula Inerna, Crus post., CST |
l |
1722 |
-24 |
-19 |
2 |
6.87 |
0.003* |
Sub-lobar, WM, Capsula Inerna, Crus post., CST |
l |
|
-28 |
-25 |
14 |
5.7 |
|
Internal capsule, Crus post., CST |
r |
408 |
24 |
-16 |
-4 |
5.69 |
0.014* |
Internal capsule, Crus post., CST |
r |
|
32 |
-17 |
-5 |
4.12 |
|
External capsule |
r |
431 |
31 |
-12 |
10 |
5.61 |
0.015* |
Follow-up FA correlation with SF36 |
|
|
|
|
|
|
|
Brainstem, Pons, CST | l | 387 | -11 | -32 | -34 | 5.37 | 0.02* |
Ordered by descending T-values. R=right; L=left, * SVC 10mm (FWE).