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. 2012 Nov 7;13:97. doi: 10.1186/1471-2156-13-97

Table 3.

Results of a genome scan for QTL associated with stress response using a variance components approach

Omy cM Trait LOD score1 P PGenomeWide2 hu23 hq24 Left flanking marker Right flanking marker
3
116
BLUP3
0.9
0.02394
1.000
0.00
0.16
OMM1263
OMM1391b
4
112
BLUP3
0.9
0.02012
0.999
0.00
0.19
OMM1582
OMM14085
4
112
EBV
0.9
0.02012
0.999
0.00
0.17
OMM1582
OMM14085
9
77
BLUP3
1.0
0.01470
0.996
0.00
0.23
OMM1089
OMM5054
10
52
EBV
0.7
0.03736
1.000
0.01
0.46
OMM1549b
OMM5312
12
39
EBV
1.9
0.00150
0.421
0.01
0.24
OMM1096
OMM11305
14
119
EBV
0.9
0.02155
1.000
0.01
0.36
OMM5153
OMM51435
16
69
BLUP3
3.3**
0.00005
0.018
0.00
0.52
OMM1150
OMM1221
17
46
EBV
1.1
0.01072
0.980
0.01
0.49
OMM5026
OMM3027
19
75
BLUP3
1.2
0.01069
0.980
0.00
0.14
OMM1739
OMM5106a5
19
114
EBV
1.0
0.01464
0.995
0.01
0.38
OMM1549a
OMM1124b
22
37
EBV
0.7
0.04031
1.000
0.01
0.12
OMM1457
BX9130595
23
31
EBV
1.1
0.01373
0.994
0.01
0.39
OMM5305
OMM1623
28
58
EBV
0.9
0.02013
0.999
0.01
0.36
OMY1013UW
OMYRGT51TUF
Sex 38 EBV 1.6 0.00371 0.743 0.01 0.43 OMM1715a BX076085

1Logarithm of odds (LOD) score was calculated as LOD = log10[L(QTL)/L(polygenic)] where L = likelihood of the model. QTL with LOD ≥ 2 was defined as suggestive QTL (*); and QTL with LOD ≥ 3 or PGenomeWide ≤ 0.05 was defined as significant QTL (**).

2The genome-wide significance level for detected QTL was estimated as PGenomeWide = 1 − (1 − P)g, where P is the nominal P-value, and g = 365 STR loci used with variance components method of QTL analysis.

3hu2 is the residual genetic variance or proportion of the total variance due to the polygenic component.

4hq2 is the heritability associated with the QTL or proportion of the total variance due to the QTL.

5The QTL flanking markers OMM5106a, OMM1408, OMM1130, BX913059 and OMM5143 had significant Mendelian segregation distortion (P <0.01) in families 2, 3, 4, 5 and 6, respectively.