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. 2012 Dec 27;7(12):e52902. doi: 10.1371/journal.pone.0052902

Table 2. Infectivity of dengue virus in Colony Forming Unit cells picked from human bone marrowa.

Days P.I. 0b 1 3 5 7 10
CFU-other cells 74c 215 198 136 124 103
Fold Increased 0 190.5 167.6 83.3 67.6 39.2
CFU-Megakaryocytes 82 114 363 145 92 26
Fold Increase 0 39.5 344.3 77.5 12.1 0
CFU-Erythroid 3530 1000 657 433 194 0
Fold Increase 0 0 0 0 0 0
a

Cells were characterized based-upon their morphology and giemsa staining characteristics.

b

Day 0 means the time point 2 hours after adsorption, in which culture supernatants were extensively washed for unbound virus. The amount of residual virus in the culture supernatant was determined and used as the baseline.

c

Quantification determined by qRT-PCR (unadjusted copy number per 140 µlof the supernatant).

d

The fold increase relative to the viral titer at Day 0, supernatant at 2 hours post-infection, was calculated.