Table 1. Hinge sites of gp120 based on gp120 ternary complex ENM calculation.
| M95-K98 | β1-α1 | Inner-outer domain interface. β-sandwich minidomain junction |
| M100-E102 | N-terminus of α1 helix helix | |
| P118-K121 | α1- β2 | Inner domain-bridging sheet boundary |
| Q203-C205 | β3- β4 | Inner domain-bridging sheet boundary |
| K231-T232 | LA | Resides on inner domain and interacts with outer domain |
| V255-L260 | LB | Inner domain-outer domain boundary, Phe43 cavity |
| I272-V275 | β10- β11 | Inner domain-outer domain interface. |
| T283-V286 | β11 | Inner domain-outer domain interface. Interacts with CD4. |
| S364-F376 | β15- α3- β16 | CD4 binding loop |
| F382-S387 | β17 | Phe43 cavity. |
| R419-K421 | β19 | Outer domain-bridging sheet boundary |
| L452-T455 | β23 | Outer domain-inner domain interface. Interacts with CD4. |
| P470-D477 | β24- α5 | Inner domain-outer domain boundary. Interacts with CD4. |