Figure 6. Impact of SOCS-1 deficiency on atherosclerotic plaque composition A.

Atherosclerotic plaques from Socs-1^−/− triple-KO (Socs-1^−/−) mice showed an increased CD68 (red);iNOS (green) double-positive cell content. B. CD68 (red); CD206 (green) double-positive cells were hardly detected. C. Atherosclerotic plaques from Socs-1^−/−triple-KO (Socs-1^−/−) mice contained slightly more MOMA-2 (red); Ly-6C (green) double-positive cells after 4 weeks of HCD as well as D. a higher number of Ly-6G positive cells (scale bar A–C: 20 µm, scale bar D:50 µm). N = 5–7 animals per group.