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. 2012 Dec 27;7(12):e52303. doi: 10.1371/journal.pone.0052303

Table 3. Consequences of pandemic A/H1N1 2009 influenza vaccination on pregnancy outcomes.

A/H1N1 2009 influenza vaccinated pregnant women Non-vaccinated pregnant women p-value
n = 320 n = 557
Gestational age (weeks) at delivery,edian (IQR) 39.5 (38.6–40.9) 39.4 (38.7–40.6) -
Delivery <37 weeks, n (%) 22 (6.9) 41 (7.4) 0.80
Onset of labour, n (%)
Spontaneous 210 (66.7) 367 (66.4)
Induction 71 (22.5) 130 (23.5) 0.92
Caesarean 34 (10.8) 56 (10.1)
Fever during labour, n (%) 26 (8.1) 53 (9.5) 0.51
Mode of delivery, n (%)
Spontaneous vaginal delivery 210 (66.7) 379 (68.3)
Instrumental vaginal delivery 34 (10.8) 47 (8.5) 0.53
Caesarean section 71 (22.5) 129 (23.2)
Delivery hemorrhage, n (%)
None 239 (90.5) 432 (90.9)
<1 liter 23 (8.7) 35 (7.4) -
>1 liter 2 (0.8) 8 (1.7)
Birth weight, g
Mean 3296.1 3282.0
<2500, n (%) 22 (6.9) 33 (6.0)
[2500–4000[, n (%) 273 (85.9) 485 (87.2) 0.81
≥4000, n (%) 23 (7.2) 38 (6.8)
Apgar score <7 at 5 min, n (%) 1 (0.3) 5 (0.9) 0.42
Infants outcome
Alive at birth 317 (99.7) 552 (99.3)
Dead before labour 1 (0.3) 3 (0.5) -
Dead during labour 0 (0.0) 1 (0.2)
Transfer to neonatal intensive care unit 31 (9.8) 61 (11.1) 0.58
Pregnancy loss 1 (0.3) 3 (0.5) 0.24
Fetal malformation 4 (1.25) 3 (0.5) 0.26
Pre eclampsia 1 (0.3) 2 (0.3) 1

Fisher’s exact test;

First infant for multiple birth.