Table 3. Consequences of pandemic A/H1N1 2009 influenza vaccination on pregnancy outcomes.
A/H1N1 2009 influenza vaccinated pregnant women | Non-vaccinated pregnant women | p-value | |
n = 320 | n = 557 | ||
Gestational age (weeks) at delivery,edian (IQR) | 39.5 (38.6–40.9) | 39.4 (38.7–40.6) | - |
Delivery <37 weeks, n (%) | 22 (6.9) | 41 (7.4) | 0.80 |
Onset of labour, n (%) | |||
Spontaneous | 210 (66.7) | 367 (66.4) | |
Induction | 71 (22.5) | 130 (23.5) | 0.92 |
Caesarean | 34 (10.8) | 56 (10.1) | |
Fever during labour, n (%) | 26 (8.1) | 53 (9.5) | 0.51 |
Mode of delivery, n (%) | |||
Spontaneous vaginal delivery | 210 (66.7) | 379 (68.3) | |
Instrumental vaginal delivery | 34 (10.8) | 47 (8.5) | 0.53 |
Caesarean section | 71 (22.5) | 129 (23.2) | |
Delivery hemorrhage, n (%) | |||
None | 239 (90.5) | 432 (90.9) | |
<1 liter | 23 (8.7) | 35 (7.4) | - |
>1 liter | 2 (0.8) | 8 (1.7) | |
Birth weight, g | |||
Mean | 3296.1 | 3282.0 | |
<2500, n (%) | 22 (6.9) | 33 (6.0) | |
[2500–4000[, n (%) | 273 (85.9) | 485 (87.2) | 0.81 |
≥4000, n (%) | 23 (7.2) | 38 (6.8) | |
Apgar score <7 at 5 min, n (%) | 1 (0.3) | 5 (0.9) | 0.42† |
Infants outcome | |||
Alive at birth | 317 (99.7) | 552 (99.3) | |
Dead before labour | 1 (0.3) | 3 (0.5) | - |
Dead during labour | 0 (0.0) | 1 (0.2) | |
Transfer to neonatal intensive care unit‡ | 31 (9.8) | 61 (11.1) | 0.58 |
Pregnancy loss | 1 (0.3) | 3 (0.5) | 0.24 |
Fetal malformation | 4 (1.25) | 3 (0.5) | 0.26 |
Pre eclampsia | 1 (0.3) | 2 (0.3) | 1 |
Fisher’s exact test;
First infant for multiple birth.