Skip to main content
. 2012 Dec 27;7(12):e52304. doi: 10.1371/journal.pone.0052304

Table 2. Timing of syngamy, 1st, 2nd, 3rd cleavage stages, cavity formation and initiation of hatching for embryos derived from the sperm of normal and obese males.

Developmental event Normal Obese P value
Cleavage (hours post-fertilisation)
Syngamy 12.63±0.09 12.86±0.07 <0.05
1st cleavage 2-cell 14.35±0.08 14.66±0.07 <0.001
2nd cleavage 3-cell 35.51±0.14 36.35±0.15 <0.0001
4-cell 36.45±0.16 37.34±0.17 <0.001
3rd cleavage 5-cell 45.99±0.17 46.92±0.19 <0.001
6-cell 46.60±0.18 47.49±0.19 <0.01
7-cell 47.33±0.19 48.16±0.20 <0.01
8-cell 47.96±0.20 48.80±0.23 <0.05
Cavitation 76.47±0.44 77.24±0.43 NS
Hatching 90.88±0.76 91.02±0.85 NS

Data are expressed as mean ± SEM. n = 200 embryos each per paternal group; NS = not significant.