Table 1. IC50 and EC50 values of the clinical LD isolates.
Isolate Code | Imipramine (µM) | |
IC50 | EC50 | |
BHU 872 (R) | 3.89±0.06 | 22.23±0.59 |
BHU 782 (R) | 3.77±0.17 | 21.01±1.13 |
BHU 814 (R) | 4.00±0.31 | 21.02±0.19 |
BHU 575 (R) | 3.83±0.24 | 22.63±2.10 |
BHU 777 (S) | 3.72±0.12 | 22.38±0.98 |
BHU 816 (S) | 3.68±0.09 | 22.42±0.98 |
IC50 and EC50 values of imipramine to recent antimony sensitive (BHU 777 and BHU 816) and antimony resistant (BHU 872, BHU 782, BHU 814 and BHU 575) clinical isolates of Leishmania donovani (LD) promastigotes.