Figure 2. Effect of lovastatin on parasitemia and survival rate after infection with PbA (n = 12–20/group).

Data on parasitemia (A) are shown as mean ± SEM. On day 6 post-infection mice were separated in two groups and one received lovastatin (10–40 mg/kg b.w.) daily for 7 days. Comparisons of C57BL6-PbA versus C57BL6-PbA treated animals (*) were significant by Mann-Withney Comparison test. There was no difference in parasitaemia when PbA and PbA-lovastatin treatment were compared (Mann-Withney Comparison test). (B) No differences in survival were observed among the groups (Log-rank (Mantel-Cox) and Gehan-Breslow-Wilcoxon tests).