Table 2.

Test characteristics of binary diagnostic tests based on free-to-total PSA ratio (FT) and hK2 (HK). The BOTH test is positive only if FT and HK are both positive; the EITHER test is positive unless either FT or HK are positive.

	FT	HK	BOTH	EITHER
Sensitivity	91%	51%	47%	94%
Specificity	40%	78%	91%	28%
Positive predictive value	35%	45%	64%	31%
Negative predictive value	92%	82%	83%	93%
Positive likelihood ratio	1.52	2.32	5.22	1.31
Negative likelihood ratio	0.23	0.63	0.58	0.21
AUC (Youden)	0.65	0.64	0.69	0.61
Brier	0.47	0.29	0.21	0.55
Correlation	0.29	0.28	0.42	0.23