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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Crit Care Med. 2013 Jan;41(1):210–218. doi: 10.1097/CCM.0b013e3182668035

Table 3.

Adjusted outcomes for seizures categories.

Variable Mortality
OR (95% CI)
p-value Worsened PCPC
OR (95% CI)
p-value
Seizure Category
 No Seizures Ref Ref Ref Ref
 Electrographic Seizures 1.3 (0.3, 5.1) 0.74 1.2 (0.4, 3.9) 0.77
 Electrographic Status Epilepticus 5.1 (1.4, 18) 0.01 17.3 (3.7, 80) <0.001
Age 1 (0.9, 1) 0.8 1 (0.99, 1.01) 0.61
Sex
 Male ref ref Ref Ref
 Female 2.5 (0.9, 6.6) .06 1.7 (0.7, 4) 0.24
Acute Neurologic Disorder Category
 Epilepsy with altered mental status following a seizure Ref Ref Ref Ref
 Hypoxic Ischemic Encephalopathy 3.6 (0.5,26) 0.2 12 (2, 72) 0.006
 Encephalitis 3.3 (0.43, 25) 0.3 40 (5.2, 304) <0.001
 Traumatic Brain Injury 0.9 (0.08, 11) 0.9 25 (3.1,197) 0.002
 Stroke 0.8 (0.05, 12) 0.85 4.7 (0.5, 430) 0.16
 Sepsis 10.6 (0.8, 137) 0.07 6.6 (0.5, 88) 0.15
 Posterior Reversible Leukoencephalopathy Syndrome - - 2.5 (0.14, 43) 0.5
 Neurosurgical Procedure 2 (0.2, 22) 0.56 4.6 (0.6, 33) 0.13
 Provoked Seizure 2.2 (0.12, 38) 0.6 0.4 (0.03, 6) 0.5
 Systemic/Metabolic 1.5 (0.1, 21) 0.77 7.4 (0.95, 52) 0.06
Prior Neurodevelopment
 Abnormal Ref Ref Ref Ref
 Normal 2.2 (0.74, 6.6) 0.16 10.5 (3.6, 31) <0.001
EEG Background Category
 Normal or Sedated-Sleep Ref Ref Ref ref
 Slow and Disorganized 4.2 (0.4, 40) 0.2 4.3 (1.08, 17) 0.04
 Discontinuous or Burst-Suppression 18 (1.5, 207) 0.02 15.8 (2.3, 107) 0.005
 Attenuated and Featureless 41 (2.7, 617) 0.007 28 (3, 244) 0.003
Indication for EEG Monitoring
 Acute encephalopathy without prior convulsion Ref Ref Ref Ref
 Acute encephalopathy with prior convulsion 0.3 (0.1, 1) 0.05 0.8 (0.27, 2.2) 0.63

CI: Confidence Interval; OR: Odds ratio; Pediatric Cerebral Performance Category: PCPC; Ref: reference group