Figure 3.
MAD-STEAM pulse sequence. The Encoding (90°-90°) section stores the magnetization along MZ with a sinusoidal encoding (MZ,enc). The encoding was refocused and data acquired at multiple mixing times (TM). These used a progressive flip angle, α[n], (43) to account for the depletion of stored magnetization by previous excitation pulses. An adiabatic double spin-echo was used following the excitation pulse and refocusing gradient to allow for symmetric sampling of the echo.