2b.

Adiposity rebound in childhood and risk of developing adult obesity

Study (#, first author) (n = 6)	Type of study (P, R)	Country	Total sample n (% male)	Adiposity rebound	Analysis/results	± (f/m)*	P value	If data adjusted
(31) Ezzahir	P	France	127 (49%)	Early adiposity rebound	anova	+ (f/m)	<0.05	Adjusted
(34) Freedman	P	USA	626 (44%)	Early adiposity rebound (<5 years)	Correlation	+ (f/m)	<0.001	Adjusted
(44) Guo	P	USA	338 (53%)	Early adiposity rebound	Regression	+ (f)	<0.001	Adjusted
					RR 2.27 (f)†	(m)	NSD
(89) Prokopec	P	Czech Republic	158 (51%)	Early adiposity rebound (<5 years)	anova	+ (f/)	<0.05
						+ (m)	<0.01
(96) Rolland cachera	P	France	164 (52%)	Early (<5 years) vs. late adiposity rebound (>7 years)	anova	+ (f)	<0.01
						+ (m)	<0.01
(130) Williams	P	New Zealand	458 (52%)	Early adiposity rebound (<5.5 years) vs. (5.5–7.5 years)	RR 5.91 of obesity at 26 years (CI – 3.03, 11.55)	+ (f/m)		Adjusted

^*(f/m) = females/males. Results are shown for adult female offspring (f), adult male offspring (m) or both (f/m).

^†A girl with a body mass index (BMI) rebound 1 year earlier has 2.27 times the risk of having a BMI >25 as a woman than a girl with a later BMI rebound (44).

anova, analysis of variance; NSD, no significant difference. No association; P, prospective study; R, retrospective study.