Table 4.
AKI misclassification rates of estimated GFR of 75 ml/min per 1.73 m2 and full multiple imputation plus serum creatinine when proportion of patients with missing data is varied
| Model | Proportion of Patients with Missing Data | ||||
|---|---|---|---|---|---|
| 10% | 20% | 40% | 60% | 80% | |
| AKI misclassification | |||||
| eGFR 75 | 11.1(9.5–12.9) | 10.7(9.5–12.0) | 11.7(10.9–12.6) | 12.7(12.0–13.5) | 14.4(13.7–15.1) |
| Full multiple imputation + SCr | 8.0(6.6–9.6) | 8.7(7.6–9.8) | 8.7(7.9–9.5) | 9.2(8.6–9.8) | 10.0(9.5–10.6) |
| AKI misclassification (eGFR < 60 ml/min per 1.73 m2) | |||||
| eGFR 75 | 44.5(36.4–53.0) | 43.0(37.2–49.0) | 40.8(37.4–44.3) | 40.5(37.9–43.0) | 41.4(39.3–43.2) |
| Full multiple imputation + SCr | 14.4(9.3–21.4) | 17.5(13.4–22.5) | 14.9(12.5–17.5) | 15.5(13.7–17.5) | 16.1(14.6–17.7) |
| AKI misclassification (eGFR ≥ 60 ml/min per 1.73 m2) | |||||
| eGFR 75 | 6.9(5.5–8.5) | 6.7(5.7–7.8) | 6.4(5.7–7.1) | 6.5(5.9–7.2) | 7.0(6.4–7.5) |
| Full multiple imputation + SCr | 7.2(5.8–8.9) | 7.6(6.5–8.7) | 7.5(6.8–8.4) | 7.8(7.1–8.5) | 8.3(7.8–9.0) |
Rates shown are for within the proportion of patients with missing data. eGFR, estimated GFR; eGFR 75, estimated GFR = 75 ml/min per 1.73 m2; SCr, serum creatinine.