Table 3.
Multiple regression analysis of factors associated with serum phosphate in MHD patients whose daily urinary output was ≤200 ml
| Variable | Group I+II: Urine ≤200 ml/d (n=94) | |||
|---|---|---|---|---|
| Univariable Model | Multivariable Model | |||
| Regression Coefficient | P | Regression Coefficient | Pa | |
| Sex (female) | 0.46 | 0.15 | ||
| Age (yr) | −0.04 | 0.01 | ||
| Dialysis vintage (yr) | 0.02 | 0.53 | ||
| GFR (ml/min per 1.73 m2) | −0.46 | 0.44 | ||
| BMI (kg/m2) | 0 0.004 | 0.93 | ||
| Albumin (g/dl) | 0.95 | 0.18 | ||
| nPNA (g/kg per day) | 2.55 | 0.003 | 1.70 | 0.02 |
| Kt/V (one dialysis session) | −0.21 | 0.73 | ||
| iPTH (pg/ml) | 0.002 | <0.001 | 0.001 | 0.001 |
| FGF-23 (pg/ml) | 0.002 | <0.001 | 0.002 | <0.001 |
| α-Klotho (pg/ml) | −0.001 | 0.44 | ||
| 1,25(OH)2D3 (pg/ml) | 0.01 | 0.80 | ||
| Dosage of calcitriol (μg/w) | −0.04 | 0.64 | ||
| Dosage of CaCO3 (g/d) | 0.24 | 0.002 | ||
MHD, maintenance hemodialysis; BMI, body mass index; nPNA, normalized protein nitrogen appearance; iPTH, intact parathyroid hormone; FGF-23, fibroblast growth factor-23.
a
P from multiple regression adjusted for nPNA, iPTH, and FGF-23. The adjusted R2 was 0.41.