Table 4.
Multiple regression analysis of factors associated with serum phosphate in MHD patients whose daily urinary output was >200 ml
Variable | Group III: Urine >200 ml/d (n=40) | |||
---|---|---|---|---|
Univariable Model | Multivariable Model | |||
Regression Coefficient | P | Regression Coefficient | Pa | |
Sex (female) | 0.86 | 0.05 | 1.13 | 0.01 |
Age (yr) | −0.06 | 0.001 | ||
Dialysis vintage (yr) | −0.15 | 0.22 | ||
GFR (ml/min per 1.73 m2) | −0.19 | 0.003 | −0.22 | 0.001 |
BMI (kg/m2) | 0.07 | 0.39 | ||
Albumin (g/dl) | 0.71 | 0.36 | ||
nPNA (g/kg per day) | −1.46 | 0.27 | ||
Kt/V (one dialysis session) | −0.49 | 0.59 | ||
iPTH (pg/ml) | 0.002 | 0.04 | ||
FGF-23 (pg/ml) | 0.002 | 0.05 | ||
α-Klotho (pg/ml) | −0.002 | 0.17 | ||
1,25(OH)2D3 (pg/ml) | 0.03 | 0.71 | ||
Dosage of calcitriol (μg/w) | 0.12 | 0.41 | ||
Dosage of CaCO3 (g/d) | 0.32 | 0.001 |
MHD, maintenance hemodialysis; BMI, body mass index; nPNA, normalized protein nitrogen appearance; iPTH, intact parathyroid hormone; FGF-23, fibroblast growth factor-23.
P from multiple regression adjusted for sex and GFR. The adjusted R2 was 0.3.