Table 1.

Characteristics of the multiple pregnancies recorded in CKD patients (ordered according to referral)

Case	Age	Kidney Disease	Week of Referral (Neph.) Week of Delivery	Chorionicity	GFR, (mL/min) Stage at Referral)	sCr at Referral and Delivery (mg/dL)	HT (Y-N) at Referral and Delivery	uPt (g/day) at Referral and Delivery	Sex and Weight	Problems SGA; Weight Discordance; NICU; Death
1	26	Membranous GNa	22–27	Dichorionic Diamniotic	150.2 Stage 1	0.43 0.77	N	5.30; 21.90	F 725 F 505	Weight discordance, NICU for bothb
2	34	IgA GNc	26–29	Dichorionic Diamniotic	103.6 Stage 1	0.70 0.85	N–Y	0.20; 12.00	M 1330 M 700	1 SGA, weight discordance, NICU for both
3	32	HT urinary anomalies	26–32	Dichorionic Diamnioticd	132.6 Stage 1	0.50 0.97	Y	0.15; 9.48	F 2000 F 1085	1 SGA, weight discordance, NICU for both
4	42	PKD	6–32	Dichorionic Diamniotic	88.5 Stage 2	1.11 1.10	Y	0.14; 0.47	M 1380 F 1875	1 SGA, weight discordance, NICU for both
5	30	Urinary tract infections	14–36	Dichorionic Diamniotic	103.1 Stage 1	0.68 0.63	N	0.00; 0.10	M 2140 M 1950	1 SGA
6	34	Renal hypoplasia	25–32	Dichorionic Diamnioticd	85.0 Stage 2	0.78 1.08	N–Y	1.48; 1.15	M 1550 F 840	1 SGA, weight discordance, NICU for both
7	35	Urinary dilatation	26–34	Trichorionic Triamnioticd	112.6 Stage 1	0.55 0.43	N	0.20; 0.35	M 2420 M 1930 M 2050	NICU for all
8	34	Single kidney	32–32	Monochorionic Diamniotic	142.7 Stage 1	0.71 0.71	N	0.23; 0.23	M 1950 M 1895	NICU for both
9	25	Previous APN (scars)	19–36	Monochorionic Diamniotic	140.4 Stage 1	0.58 0.56	N	0.00; 0.30	M 2015 M 2540	Weight discordance
10	33	Urinary dilatation	25–34	Dichorionic Diamnioticd	148.7 Stage 1	0.45 0.66	N–Y	0.00; 0.10	F 1910 M 1960	None
11	35	Kidney stones	18–37	Dichorionic Diamniotic	109.2 Stage 1	0.59 0.63	N	0.20; 0.10	F 2470 F 2630	None
12	45	Sponge kidney	19–33	Dichorionic Triamnioticd	171.8 Stage 1	0.62 0.62	Y	0.38; 0.41	M 1305 F 1540	1 miscarriage at 17 weeks, 1 SGA, NICU for both
13	32	Nephro-calcinosis	33–36	Dichorionic Diamniotic§	117.6 Stage 1	0.65 0.90	Y	0.10; 0.10	M 2660 F2440	None
14	41	Kidney stones	22–36	Dichorionic Diamniotic	152.8 Stage 1	0.52 0.52	N	0.30; 0.30	F 2200 F 2250	None
15	31	PKD	16–36	Monochorionic Diamniotic	134.3 Stage 1	0.45 0.52	N	0.00; 0.20	M 2190 M 2410	NICU for both
16	32	Diabetic nephropathy	21–32	Dichorionic Diamniotic	122.6 Stage 1	0.52 0.65	N–Y	5.42; 10.00	M 1270 F 1275	1 SGA, NICU for both, death of male twin
17	36	Kidney transplant	5	Dichorionic Diamniotic	47.2 Stage 3	1.30 1.20	N	0.37; 0.40	-	Miscarriage at 8 weeks
18	32	Familial nephropathy	20–32	Dichorionic Diamniotic	69.8 Stage 2	1.06 1.39	Y	0.18; 4.00	M 1200 F 1000	2 SGA, NICU for both, death of male twin
19	28	GN or PEe	24–ongoing	Monochorionic Diamniotic	119 Stage 1	Ongoing	Y	1.52;	--	Ongoing
20	38	PKD	19–ongoing	Dichorionic Diamniotic	92.7 Stage 1	Ongoing	N	0.10;	--	Ongoing

GN, glomerulonephritis; PKD, polycystic kidney disease; PE, pre-eclampsia; GFR, glomerular filtration rate; HT, hypertension; uPt, 24 hours proteinuria: APN, acute pyelonephritis; Spont, spontaneous pregnancy; SGA, small for gestational age; NICU, Neonatal Intensive Care Unit; Weight discordance, at least 20% weight discrepancy; Neph, Nephrology Unit.

^aBiopsy after delivery.

^bSGA not assessed (delivery before the 28^th week).

^cPreviously classified as acute GN.

^dAssisted fertilization.

^eReferred in differential diagnosis with PE.