Table 2.
Univariate analysis of factors related to postoperative liver insufficiency
| Variables | Patients with liver insufficiency (n = 17) | Patients without liver insufficiency (n = 410) | P value |
| Sex (male/female) | 17/0 | 345/65 | 0.075 |
| Age (yr) | 57.6 ± 7.1 | 50.8 ± 10.4 | 0.008 |
| < 60 | 10 | 325 | |
| ≥ 60 | 7 | 85 | |
| Tumor size (cm) | 6.6 ± 5.0 | 6.2 ± 3.9 | 0.664 |
| ≥ 10 | 4 | 79 | |
| < 10 | 13 | 331 | |
| WBC (× 109/L) | 5.2 ± 1.9 | 5.5 ± 1.8 | 0.581 |
| PLT(× 109/L) | 146.0 ± 88.2 | 161.1 ± 65.4 | 0.357 |
| PT (s) | 12.5 ± 1.3 | 12.2 ± 4.9 | 0.816 |
| Total bilirubin (μmol/L) | 16.3 ± 5.7 | 14.5 ± 5.8 | 0.205 |
| Albumin (g/L) | 40.2 ± 4.3 | 42.0 ± 4.3 | 0.074 |
| Prealbumin (mg/dL) | 191.4 ± 59.6 | 217.9 ± 61.1 | 0.049 |
| < 170 | 8 | 84 | |
| ≥ 170 | 9 | 326 | |
| ALT (IU/L) | 52.2 ± 38.0 | 47.2 ± 43.9 | 0.647 |
| ≥ 100 | 3 | 29 | |
| < 100 | 14 | 381 | |
| Viral background | 0.222 | ||
| HBV and/or HCV | 4 | 54 | |
| None | 13 | 356 | |
| Liver cirrhosis | 0.182 | ||
| No | 5 | 188 | |
| Yes | 12 | 222 | |
| Ascites | 0.415 | ||
| Little | 3 | 46 | |
| No | 14 | 364 | |
| Esophageal varices | 0.251 | ||
| Present | 4 | 56 | |
| Absent | 13 | 354 | |
| Types of liver resection | 0.130 | ||
| Minor ≤ 3 liver segments | 12 | 346 | |
| Major ≥ 4 liver segments | 5 | 64 | |
| Inflow blood occlusion time (min) | 17.2 ± 6.2 | 15.7 ± 8.0 | 0.438 |
| > 20 | 4 | 102 | |
| ≤ 20 | 13 | 308 | |
| Blood loss (mL) | 200 (50-5500) | 200 (50-2800) | 0.362 |
| ≥ 800 | 1 | 36 | |
| < 800 | 16 | 374 | |
| Blood transfusion | 0.558 | ||
| Yes | 1 | 42 | |
| No | 16 | 368 |
WBC: White blood cell; PLT: Platelet; PT: Prothrombin time; ALT: Alanine aminotransferase; HBV: Hepatitis B virus; HCV: Hepatitis C virus.