Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Nov 7;287(53):44330–44337. doi: 10.1074/jbc.M112.417980

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 4. — Fluorescence anisotropy measurements of WT Dmp53 and its mutants. DNA binding to 5-fluorescein-labeled double-stranded 30-mers containing either the recognition element from the gadd45 promoter (RE, closed circles) or a randomly generated sequence of 30 bases (RAN, open circles) was measured. A, p53 variants that bind the RE with high affinity. Green, QMHp53; blue, WT Dmp53; red, Dmp53 R235S mutant. B, p53 variants that abrogated the affinity to the RE. Blue, Dmp53 R155H; green, G233S; red, K259H; black, R268W.