TABLE 1 .
Statistics of P. jirovecii and P. carinii nuclear and mitochondrial genomes
| Characteristic | Result |
|
|---|---|---|
| P. jirovecii | P. cariniia | |
| Assembly | ||
| Assembly size (Mb) | 8.1 | 6.3 |
| Mean 454 read depth | 36 | NAb |
| Mean Illumina read depth | 1,315 | NA |
| No. of contigs | 358 | 4,278 |
| N50 (kb) | 41.6 | 2.2 |
| Mean GC content (%) | 28.4 | 32.5 |
| Annotation | ||
| No. of CDSs | 3,898 | 4,591c |
| Coding regions (%) | 68.9 | 50.0 |
| No. of KEGG orthologsd | 269 | 252 |
| No. of tRNA genes | 77e | 36f |
| Mean gene length (bp) | 1,472 | 891 |
| Mean exon length (nt) | 211 | 223 |
| Mean no. of introns per gene | 4.5 | 2.3 |
| Mean intron length (nt) | 61 | 54 |
| Repeat density (%) | 9.86 | 5.71 |
| Mitochondrial genome | ||
| Assembly size (kb) | 27 | 23g |
| No. of contigs | 3 | 1 |
| GC content in whole genome (%) | 29.5 | 31.1 |
| GC content in coding genes (%) | 32.5 | 30.9 |
| No. of protein coding genes (CDSs) | 17 | 17 |
| No. of rRNA genes | 2 | 2 |
| No. of tRNA genes | 12 | 20 |
The P. carinii assembly was downloaded from the Pneumocystis genome project website (http://pgp.cchmc.org/) and corresponds to the sequences published by Slaven et al. (15). This assembly is known to be incomplete.
Not applicable.
Some of these peptides were derived from incomplete CDSs located at the extremity of a contig. Hence, the numbers of predicted peptides provide only a rough estimation of the proteome size.
The number of KEGG orthologs was computed as described previously (4).
Not including pseudo tRNAs.
Only complete copies are shown; the total number of tRNAs in the genome may be more important.
P. carinii mitochondrion data were computed from the published genome (16).