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Model Showing Endomembrane Trafficking Processes Regulated by KEG.
KEG resides on the TGN/EE where it regulates secretion of defense proteins from the Golgi to the apoplast and trafficking of PM proteins through MVBs to the vacuole (red arrows). KEG does not appear to play a role in endocytosis from the PM (blue arrow), in the formation of autophagosomes or their delivery to the vacuole, nor in the delivery of at least some soluble cargo proteins to the vacuole, such as GOLD36/MVP1.
