Figure 5.

Schematic representation of the effect of non-specific LINKs between the islets of functionally LINKed postsynapses that can lead to cognitive dysfunction, changes in oscillating waveforms, and result in meaningful hallucinations. (A) Cross-section through large number of postsynapses assuming that they are in the same plane. Thin arrow: single postsynapse; Thick arrow: islet of LINKed postsynapses. Note that two of the islets are interconnected in comparison with those shown in Figure 4B. (B) This figure is modified from Figure 4C. Cross-section through two islets of LINKed postsynapses I₁ and I₂ (also shown in Figure 4C) that are non-specifically LINKed. This results in the formation of a combination of semblances S₁ and S₂, changing the conformation of semblances of retrieved memories (as shown in Figure 4C). Note that the neurons N₁ and N₂ that otherwise receive sub-threshold stimuli now start receiving EPSPs from the islet I₁. This leads to the activation of the neurons N1 and N2, resulting in the activation of islets of functionally LINKed postsynapses I₃ and I₄, eliciting semblances (S₃ and S₄) of previously associatively learned items or events, producing meaningful hallucinations. Note that background oscillatory neuronal activity was proposed to result in semblance formation from a large number of functionally LINKed postsynapses, resulting in C-semblance responsible for consciousness (Vadakkan, 2010). Non-specific LINK induced activation of large number of neurons similar to N1 and N2 can lead to a change in oscillatory neuronal activity (not shown) changing the conformation of C-semblance (not shown) and produce alterations in conscious perception of items or events.