Figure 1.

Representative traces of EPSPs [intracellular (intracel)] (A, C, E) and evoked potentials [extracellular (extracel)] (B, D, F) under the following conditions: before (dotted line traces) and after (solid line traces) acute HX (A, B); chronic HX and P'ase treatment (C, D); chronic HX and Ch'ase treatment (E, F). Inset (B) shows position of stimulation (st)/recording (rec.) electrodes with respect to HX. The extracellular responses consist of two components: the early biphasic arriving volley (measured between the arrows) and the later downward extracellular synaptic response (measured from baseline to peak). Note that P'ase did not reverse the effects of chronic hemisection in attenuating the contralateral volley, whereas Ch'ase did partially attenuate it (see Results).