Table 1.

Genetic classification of CMT

Inheritance	Demyelinating forms		Intermediate forms		Axonal forms
	form	gene	OMIM	form	gene	OMIM	form	gene	OMIM
Autosomal dominant	CMT1A/CMT1E CMT1B CMT1C CMT1D CMT1F	PMP22 MPZ LITAF EGR2 NEFL	601097 159440 603795 129010 162280	DI-CMTA DI-CMTB DI-CMTC DI-CMTD DI-CMTE Slow SNV	? DNM2 YARS MPZ INF2 ARHGEF10	602378 603623 159440 610982 608136	CMT2A1/2 CMT2B CMT2C CMT2D CMT2E CMT2F CMT2G CMT2I/2J CMT2K CMT2L CMT2M CMT2N CMT2O CMT2P	MFN2/KIF1B RAB7 TRPV4 GARS NEFL HSP27 (HSPB1) ? MPZ GDAP1 HSP22 (HSPB8) DNM2 AARS DYNC1H1 LRSAM1	608507/605995 602298 605427 600287 162280 602195   159440 606598 608014 602378 601065 600112 610933
Autosomal recessive	CMT4A CMT4B1 CMT4B2 CMT4C CMT4D (HMSNL) CMT4E CMT4F CMT4G (HMSNR) CMT4H CMT4J	GDAP1 MTMR2 MTMR13 (SBF2) SH3TC2 NDRG1 EGR2/MPZ PRX HK1 FGD4 FIG4	606598 603557 607697 608206 605262 129010/159440 605725   611104 609390	RI-CMTA	GDAPl	606598	ARCMT2A2 CMT2B1 CMT2B2 CMT2H CMT2P	MFN2 LMNA MED25 GDAP1 LRSAM1	608507 150330 610197 606598 610933
X-linked dominant				CMTX1	GjBl	304040
X-linked recessive				CMTX2 CMTX3 CMTX4 CMTX5	? ? ? PRPS1	311850

Genes KARS [McLaughlin et al., 2010] and CTDP1 [Varon et al., 2003] were not considered because they are associated with syndromic conditions for which peripheral neuropathy represents only a part of the pathology. ? = Disease gene is unknown.