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. Author manuscript; available in PMC: 2012 Dec 28.
Published in final edited form as: Semin Cell Dev Biol. 2009 Oct 17;21(1):2–10. doi: 10.1016/j.semcdb.2009.10.001

Fig. 2. Anti-DNMT1 immunohistochemistry in human intestinal type gastric cancer.

Fig. 2

A. 10×; B. 40×. Almost all DNMT1 positive cells are seen in the tumor epithelium and not in the stroma. Thus while DNMT1 mRNA expression can be detected in the stromal cells by sensitive RT-PCR, the protein levels appear much reduced relative to the levels in the malignant epithelial cells. On serial sections the stromal cells were strongly αSMA positive (not shown).