Table 5.
Simulated Outcomes of 3 Models Representing the 25 and Older US General Population: a) The Background CRC Incidence by Age Group per 100,000 Person Years and b) the Maximum Clinical Incidence Reduction (MCLIR65) after Complete Removal of Preclinical Cancer and Adenomas at Age 65 for 5-Year Periods and until Age 80, by Age Group and by Period Since Complete Removal.
| Age | 50–54 | 55–59 | 60–64 | 65–69 | 70–74 | 75–79 | 80–84 | 65–79 |
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| (a) | Background incidence | |||||||
| MISCAN | 51 | 88 | 139 | 208 | 286 | 370 | 440 | 279 |
| CRC-SPIN | 52 | 85 | 127 | 180 | 247 | 327 | 424 | 243 |
| SimCRC | 61 | 96 | 142 | 202 | 277 | 357 | 424 | 271 |
| (b) | MCLIR65 | ||||
|---|---|---|---|---|---|
|
| |||||
| Time since complete removal (years) | 0–5 | 5–10 | 10–15 | 15–20 | 0–15 |
| MISCAN, % | 84 | 55 | 30% | 17% | 51% |
| CRC-SPIN, % | 100 | 99 | 92% | 77% | 90% |
| SimCRC, % | 100 | 97 | 86% | 74% | 88% |