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. Author manuscript; available in PMC: 2013 Mar 15.
Published in final edited form as: Cell Host Microbe. 2012 Mar 15;11(3):290–297. doi: 10.1016/j.chom.2012.01.016

Figure 4. M45mutRHIM virus attenuation in vivo is reversed in DAI−/− mice.

Figure 4

(A) Footpad swelling induced by parental WT or M45mutRHIM MCMV infection. Footpad thickness of C57BL/6 control (top) and DAI−/− (bottom) mice inoculated with 106 pfu was measured with a digital caliper, and mean values plotted at the indicated times over a 14 day time course (n=7–9 animals/group). (B–D) Viral titers from spleen (B), liver (C), and SGs (D) of control (C57BL/6), RIP3−/−, and DAI−/− mice infected via intraperitoneal inoculation with 106 pfu of indicated virus and harvested at the indicated time (n= 5–10 animals/group). Error bars, SEM. See also related Figure S4.