. Author manuscript; available in PMC: 2012 Dec 28.

Published in final edited form as: Angew Chem Int Ed Engl. 2011 Apr 8;50(20):4689–4691. doi: 10.1002/anie.201101066

Table 1.

Click reactions of various terminal alkynes with twelve-fold azido closomer 3 using CuI and DIPEA in CH₃CN-THF (1:1).

Entry	Alkyne	Product	Yield[%]^[a]
4a			72
4b			74
4c			70
4d			59
4e			78
4f			79
4g			80^[b]
4h			62

^[a]

all yields after purification

^[b]

crude yield