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. 2012 Dec 28;7(12):e52707. doi: 10.1371/journal.pone.0052707

Figure 2. Expression of genes/proteins associated with the KEGG pathways in fibroblastic meningiomas and arachnoidal tissue.

Figure 2

qRT-PCR experiments were performed to confirm the expression of genes in 10 fibroblastic meningiomas (including the 3 tested samples in microarray) and 3 arachnoidal tissues. When expression of the genes in arachnoidal tissue was set to 1, up-regulated (A) and down-regulated (B) folds of the genes in fibroblastic meningiomas are shown in each graph by using microarray and qRT-PCR. *P<0.05, **P<0.01, ***P<0.001. Western blotting determined total Akt and phosphorylated Akt (p-Akt Thr 308) in fibroblastic meningiomas and arachnoidal tissue (C). GAPDH expression was used as controls. Key words: FM, fibroblastic meningioma; BAT, brain arachnoidal tissue.